View in EDS HTML Full Text PDF Full Text

APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.

Saved in:
Bibliographic Details
Title: APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
Authors: Tran KM; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Kwang NE; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Butler CA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Gomez-Arboledas A; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Kawauchi S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Mar C; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Chao D; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Barahona RA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Da Cunha C; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Tsourmas KI; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Shi Z; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Wang S; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Collins S; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Walker A; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Shi KX; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Alcantara JA; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Neumann J; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Duong DM; ARCProteomics, Atlanta, GA, 30322, USA., Seyfried NT; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, 30322, USA., Tenner AJ; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Department of Molecular Biology & Biochemistry, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA.; Department of Pathology and Laboratory Medicine, University of California, Irvine, CA, 92697, USA., LaFerla FM; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Hohsfield LA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Swarup V; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, CA, 92697, USA., MacGregor GR; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA. gmacg@uci.edu.; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA. gmacg@uci.edu., Green KN; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA. kngreen@uci.edu.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA. kngreen@uci.edu.
Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Jan 22; Vol. 20 (1), pp. 9. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39844286
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Tran+KM%22">Tran KM</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Kwang+NE%22">Kwang NE</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Butler+CA%22">Butler CA</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Arboledas+A%22">Gomez-Arboledas A</searchLink>; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Kawauchi+S%22">Kawauchi S</searchLink>; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Mar+C%22">Mar C</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Chao+D%22">Chao D</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Barahona+RA%22">Barahona RA</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Da+Cunha+C%22">Da Cunha C</searchLink>; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Tsourmas+KI%22">Tsourmas KI</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Z%22">Shi Z</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Collins+S%22">Collins S</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Walker+A%22">Walker A</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Shi+KX%22">Shi KX</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Alcantara+JA%22">Alcantara JA</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Neumann+J%22">Neumann J</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA.<br /><searchLink fieldCode="AU" term="%22Duong+DM%22">Duong DM</searchLink>; ARCProteomics, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Seyfried+NT%22">Seyfried NT</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Tenner+AJ%22">Tenner AJ</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Department of Molecular Biology & Biochemistry, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA.; Department of Pathology and Laboratory Medicine, University of California, Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22LaFerla+FM%22">LaFerla FM</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Hohsfield+LA%22">Hohsfield LA</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.<br /><searchLink fieldCode="AU" term="%22Swarup+V%22">Swarup V</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22MacGregor+GR%22">MacGregor GR</searchLink>; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA. gmacg@uci.edu.; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA. gmacg@uci.edu.<br /><searchLink fieldCode="AU" term="%22Green+KN%22">Green KN</searchLink>; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA. kngreen@uci.edu.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA. kngreen@uci.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101266600%22">Molecular neurodegeneration</searchLink> [Mol Neurodegener] 2025 Jan 22; Vol. 20 (1), pp. 9. <i>Date of Electronic Publication: </i>2025 Jan 22.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101266600 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1750-1326 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217501326%22">17501326 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurodegener <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39844286
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s13024-024-00793-x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 9
    Titles:
      – TitleFull: APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tran KM
      – PersonEntity:
          Name:
            NameFull: Kwang NE
      – PersonEntity:
          Name:
            NameFull: Butler CA
      – PersonEntity:
          Name:
            NameFull: Gomez-Arboledas A
      – PersonEntity:
          Name:
            NameFull: Kawauchi S
      – PersonEntity:
          Name:
            NameFull: Mar C
      – PersonEntity:
          Name:
            NameFull: Chao D
      – PersonEntity:
          Name:
            NameFull: Barahona RA
      – PersonEntity:
          Name:
            NameFull: Da Cunha C
      – PersonEntity:
          Name:
            NameFull: Tsourmas KI
      – PersonEntity:
          Name:
            NameFull: Shi Z
      – PersonEntity:
          Name:
            NameFull: Wang S
      – PersonEntity:
          Name:
            NameFull: Collins S
      – PersonEntity:
          Name:
            NameFull: Walker A
      – PersonEntity:
          Name:
            NameFull: Shi KX
      – PersonEntity:
          Name:
            NameFull: Alcantara JA
      – PersonEntity:
          Name:
            NameFull: Neumann J
      – PersonEntity:
          Name:
            NameFull: Duong DM
      – PersonEntity:
          Name:
            NameFull: Seyfried NT
      – PersonEntity:
          Name:
            NameFull: Tenner AJ
      – PersonEntity:
          Name:
            NameFull: LaFerla FM
      – PersonEntity:
          Name:
            NameFull: Hohsfield LA
      – PersonEntity:
          Name:
            NameFull: Swarup V
      – PersonEntity:
          Name:
            NameFull: MacGregor GR
      – PersonEntity:
          Name:
            NameFull: Green KN
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 22
              M: 01
              Text: 2025 Jan 22
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1750-1326
          Numbering:
            – Type: volume
              Value: 20
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Molecular neurodegeneration
              Type: main
ResultId 1