Drosophila modeling to identify causative genes and reveal the underlying molecular mechanisms for primary ovarian insufficiency.

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Title: Drosophila modeling to identify causative genes and reveal the underlying molecular mechanisms for primary ovarian insufficiency.
Authors: Ma Y; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China.; Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining, 314400, China., Liu Y; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China., Xu M; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China., Yin X; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China., Hu C; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining, 314400, China., Yang X; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China., Ge W; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China. wanzhongge@zju.edu.cn.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China. wanzhongge@zju.edu.cn.; Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China. wanzhongge@zju.edu.cn.; Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining, 314400, China. wanzhongge@zju.edu.cn.; Zhejiang Provincial Clinical Research Center for Child Health, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China. wanzhongge@zju.edu.cn.; Cancer Center, Zhejiang University, Hangzhou, 310058, Zhejiang, China. wanzhongge@zju.edu.cn.
Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2025 Feb; Vol. 103 (2), pp. 239-253. Date of Electronic Publication: 2025 Jan 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1440 (Electronic) Linking ISSN: 09462716 NLM ISO Abbreviation: J Mol Med (Berl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1440
DOI:10.1007/s00109-025-02516-1