Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study.

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Title: Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study.
Authors: Finn RS; University of California Los Angeles (UCLA), Los Angeles, CA, USA. Electronic address: rfinn@mednet.ucla.edu., Ryoo BY; Asan Medical Center, Seoul, South Korea., Hsu CH; National Taiwan University Hospital, Taipei, Taiwan., Li D; City of Hope Comprehensive Cancer Center, Los Angeles, CA, USA., Burgoyne AM; UC San Diego, San Diego, CA, USA., Cotter C; Genentech, South San Francisco, CA, USA., Badhrinarayanan S; Genentech, South San Francisco, CA, USA., Wang Y; Genentech, South San Francisco, CA, USA., Yin A; Roche (China) Holding, Shanghai, China., Edubilli TR; Roche Products, Welwyn Garden City, UK., Mahrus S; Genentech, South San Francisco, CA, USA., Secrest MH; Genentech, South San Francisco, CA, USA., Shemesh CS; Genentech, South San Francisco, CA, USA., Yu N; Genentech, South San Francisco, CA, USA., Hack SP; Genentech, South San Francisco, CA, USA., Cha E; Genentech, South San Francisco, CA, USA., Gane E; University of Auckland, Auckland, New Zealand.
Source: The Lancet. Oncology [Lancet Oncol] 2025 Feb; Vol. 26 (2), pp. 214-226. Date of Electronic Publication: 2025 Jan 21.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-5488
DOI:10.1016/S1470-2045(24)00679-X