Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study.
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| Title: | Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study. |
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| Authors: | Finn RS; University of California Los Angeles (UCLA), Los Angeles, CA, USA. Electronic address: rfinn@mednet.ucla.edu., Ryoo BY; Asan Medical Center, Seoul, South Korea., Hsu CH; National Taiwan University Hospital, Taipei, Taiwan., Li D; City of Hope Comprehensive Cancer Center, Los Angeles, CA, USA., Burgoyne AM; UC San Diego, San Diego, CA, USA., Cotter C; Genentech, South San Francisco, CA, USA., Badhrinarayanan S; Genentech, South San Francisco, CA, USA., Wang Y; Genentech, South San Francisco, CA, USA., Yin A; Roche (China) Holding, Shanghai, China., Edubilli TR; Roche Products, Welwyn Garden City, UK., Mahrus S; Genentech, South San Francisco, CA, USA., Secrest MH; Genentech, South San Francisco, CA, USA., Shemesh CS; Genentech, South San Francisco, CA, USA., Yu N; Genentech, South San Francisco, CA, USA., Hack SP; Genentech, South San Francisco, CA, USA., Cha E; Genentech, South San Francisco, CA, USA., Gane E; University of Auckland, Auckland, New Zealand. |
| Source: | The Lancet. Oncology [Lancet Oncol] 2025 Feb; Vol. 26 (2), pp. 214-226. Date of Electronic Publication: 2025 Jan 21. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II |
| Journal Info: | Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39855251 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Finn+RS%22">Finn RS</searchLink>; University of California Los Angeles (UCLA), Los Angeles, CA, USA. Electronic address: rfinn@mednet.ucla.edu.<br /><searchLink fieldCode="AU" term="%22Ryoo+BY%22">Ryoo BY</searchLink>; Asan Medical Center, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Hsu+CH%22">Hsu CH</searchLink>; National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; City of Hope Comprehensive Cancer Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Burgoyne+AM%22">Burgoyne AM</searchLink>; UC San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cotter+C%22">Cotter C</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Badhrinarayanan+S%22">Badhrinarayanan S</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yin+A%22">Yin A</searchLink>; Roche (China) Holding, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Edubilli+TR%22">Edubilli TR</searchLink>; Roche Products, Welwyn Garden City, UK.<br /><searchLink fieldCode="AU" term="%22Mahrus+S%22">Mahrus S</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Secrest+MH%22">Secrest MH</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shemesh+CS%22">Shemesh CS</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+N%22">Yu N</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hack+SP%22">Hack SP</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cha+E%22">Cha E</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gane+E%22">Gane E</searchLink>; University of Auckland, Auckland, New Zealand. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100957246%22">The Lancet. Oncology</searchLink> [Lancet Oncol] 2025 Feb; Vol. 26 (2), pp. 214-226. <i>Date of Electronic Publication: </i>2025 Jan 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lancet+Pub%2E+Group%22">Lancet Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100957246 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-5488 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214702045%22">14702045 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39855251 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S1470-2045(24)00679-X Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 214 Titles: – TitleFull: Tiragolumab in combination with atezolizumab and bevacizumab in patients with unresectable, locally advanced or metastatic hepatocellular carcinoma (MORPHEUS-Liver): a randomised, open-label, phase 1b-2, study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Finn RS – PersonEntity: Name: NameFull: Ryoo BY – PersonEntity: Name: NameFull: Hsu CH – PersonEntity: Name: NameFull: Li D – PersonEntity: Name: NameFull: Burgoyne AM – PersonEntity: Name: NameFull: Cotter C – PersonEntity: Name: NameFull: Badhrinarayanan S – PersonEntity: Name: NameFull: Wang Y – PersonEntity: Name: NameFull: Yin A – PersonEntity: Name: NameFull: Edubilli TR – PersonEntity: Name: NameFull: Mahrus S – PersonEntity: Name: NameFull: Secrest MH – PersonEntity: Name: NameFull: Shemesh CS – PersonEntity: Name: NameFull: Yu N – PersonEntity: Name: NameFull: Hack SP – PersonEntity: Name: NameFull: Cha E – PersonEntity: Name: NameFull: Gane E IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2025 Feb Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1474-5488 Numbering: – Type: volume Value: 26 – Type: issue Value: 2 Titles: – TitleFull: The Lancet. Oncology Type: main |
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