Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts.

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Title: Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts.
Authors: Luckett AM; University of Exeter College of Medicine and Health, Exeter, UK., Oram RA; University of Exeter College of Medicine and Health, Exeter, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Deutsch AJ; Programs in Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Metabolism, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ortega HI; Department of Pediatrics, Division of Endocrinology, Stanford School of Medicine, Stanford University, CA, USA., Fraser DP; University of Exeter College of Medicine and Health, Exeter, UK., Ashok K; Programs in Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Metabolism, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA., Manning AK; Programs in Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Metabolism, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA., Mercader JM; Programs in Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Metabolism, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Pediatrics, Division of Endocrinology, Stanford School of Medicine, Stanford University, CA, USA., Rivas M; Department of Biomedical Data Sciences, Stanford School of Medicine, Stanford University, CA, USA., Udler MS; Programs in Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Metabolism, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Weedon MN; University of Exeter College of Medicine and Health, Exeter, UK., Gloyn AL; Department of Pediatrics, Division of Endocrinology, Stanford School of Medicine, Stanford University, CA, USA.; Department of Genetics, Stanford School of Medicine, Stanford University, CA, USA.; Stanford Diabetes Research Center, Stanford School of Medicine, Stanford University, CA, USA., Sharp SA; Department of Pediatrics, Division of Endocrinology, Stanford School of Medicine, Stanford University, CA, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Jan 17. Date of Electronic Publication: 2025 Jan 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.1101/2025.01.16.25320691