View in EDS HTML Full Text PDF Full Text

Protective effect of valsartan alone and in combination with neprilysin inhibitor (valsartan + sacubitril) against hepatic ischemia-reperfusion injury: targeting angiotensin II receptor-neprilysin and modulating SMAD-4/NF-κβ/JNK pathways in rats.

Saved in:
Bibliographic Details
Title: Protective effect of valsartan alone and in combination with neprilysin inhibitor (valsartan + sacubitril) against hepatic ischemia-reperfusion injury: targeting angiotensin II receptor-neprilysin and modulating SMAD-4/NF-κβ/JNK pathways in rats.
Authors: Elsayed Abouzed DE; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt. deiaaabozed@pharm.sohag.edu.eg., Bafail DA; Department of Clinical Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Refaie SM; Department of Biomedical Science, Faculty of Medicine, King Faisal University, 36375, Hofuf, Saudi Arabia., Aboelez MO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt., Elsayed AA; Clinical Pharmacy, Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt., Mallasiy LO; Muhayil Asir, Applied College, King Khalid University, 61913, Abha, Saudi Arabia., Bayoumy NMK; Department of Physiology, College of Medicine, King Saud University, 12271, Riyadh, Saudi Arabia., Hagar H; Department of Physiology, College of Medicine, King Saud University, 12271, Riyadh, Saudi Arabia.; Department of Pharmacology, College of Pharmacy, Zagazig University, Zagazig, 44511, Egypt.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Jul; Vol. 398 (7), pp. 8797-8811. Date of Electronic Publication: 2025 Jan 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39869188
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Protective effect of valsartan alone and in combination with neprilysin inhibitor (valsartan + sacubitril) against hepatic ischemia-reperfusion injury: targeting angiotensin II receptor-neprilysin and modulating SMAD-4/NF-κβ/JNK pathways in rats.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Elsayed+Abouzed+DE%22">Elsayed Abouzed DE</searchLink>; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt. deiaaabozed@pharm.sohag.edu.eg.<br /><searchLink fieldCode="AU" term="%22Bafail+DA%22">Bafail DA</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Refaie+SM%22">Refaie SM</searchLink>; Department of Biomedical Science, Faculty of Medicine, King Faisal University, 36375, Hofuf, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aboelez+MO%22">Aboelez MO</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.<br /><searchLink fieldCode="AU" term="%22Elsayed+AA%22">Elsayed AA</searchLink>; Clinical Pharmacy, Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.<br /><searchLink fieldCode="AU" term="%22Mallasiy+LO%22">Mallasiy LO</searchLink>; Muhayil Asir, Applied College, King Khalid University, 61913, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Bayoumy+NMK%22">Bayoumy NMK</searchLink>; Department of Physiology, College of Medicine, King Saud University, 12271, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hagar+H%22">Hagar H</searchLink>; Department of Physiology, College of Medicine, King Saud University, 12271, Riyadh, Saudi Arabia.; Department of Pharmacology, College of Pharmacy, Zagazig University, Zagazig, 44511, Egypt.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2025 Jul; Vol. 398 (7), pp. 8797-8811. <i>Date of Electronic Publication: </i>2025 Jan 27.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39869188
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00210-025-03820-w
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 8797
    Titles:
      – TitleFull: Protective effect of valsartan alone and in combination with neprilysin inhibitor (valsartan + sacubitril) against hepatic ischemia-reperfusion injury: targeting angiotensin II receptor-neprilysin and modulating SMAD-4/NF-κβ/JNK pathways in rats.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Elsayed Abouzed DE
      – PersonEntity:
          Name:
            NameFull: Bafail DA
      – PersonEntity:
          Name:
            NameFull: Refaie SM
      – PersonEntity:
          Name:
            NameFull: Aboelez MO
      – PersonEntity:
          Name:
            NameFull: Elsayed AA
      – PersonEntity:
          Name:
            NameFull: Mallasiy LO
      – PersonEntity:
          Name:
            NameFull: Bayoumy NMK
      – PersonEntity:
          Name:
            NameFull: Hagar H
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2025 Jul
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1432-1912
          Numbering:
            – Type: volume
              Value: 398
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology
              Type: main
ResultId 1