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Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.

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Title: Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
Authors: Scott TM; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Arnold LM; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Powers JA; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., McCann DA; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Rowe AB; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Christensen DE; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Pereira MJ; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Zhou W; Department of Immunology and Microbiology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China., Torrez RM; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Iwasa JH; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Kranzusch PJ; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America., Sundquist WI; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Johnson JS; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2025 Jan 28; Vol. 21 (1), pp. e1012206. Date of Electronic Publication: 2025 Jan 28 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
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  Data: <searchLink fieldCode="AU" term="%22Scott+TM%22">Scott TM</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Arnold+LM%22">Arnold LM</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Powers+JA%22">Powers JA</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22McCann+DA%22">McCann DA</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Rowe+AB%22">Rowe AB</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Christensen+DE%22">Christensen DE</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Pereira+MJ%22">Pereira MJ</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Department of Immunology and Microbiology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Torrez+RM%22">Torrez RM</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Iwasa+JH%22">Iwasa JH</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Kranzusch+PJ%22">Kranzusch PJ</searchLink>; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Sundquist+WI%22">Sundquist WI</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Johnson+JS%22">Johnson JS</searchLink>; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
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