Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum.
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| Title: | Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum. |
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| Authors: | Fernández Arias J; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Brum WS; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden.; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, Brazil., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden., Therriault J; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada.; Faculty of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada., Servaes S; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Wang YT; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Aumont E; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Département de Psychologie, Université du Quebec á Montréal, Montreal, Quebec H2L 2C4, Canada., Rahmouni N; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Macedo AC; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Quispialaya KM; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Hosseini SA; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Kunach P; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Diamond Lab, University of Texas Southwestern, Dallas, TX 75390, USA., Jia WL; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Chan T; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Trudel L; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Hall B; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Zheng Y; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Mohapatra S; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Mathotaarachchi SS; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada., Vitali P; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada., Tissot C; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Lawrence Berkeley National Laboratory, Department of Cellular and Tissue Imaging, Berkeley, CA 94720, USA., Bezgin G; The NeuroPM Lab, Montreal Neurological Institute, Montreal, Quebec, H3A 2B4, Canada., Iturria-Medina Y; The NeuroPM Lab, Montreal Neurological Institute, Montreal, Quebec, H3A 2B4, Canada., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden.; Banner Sun Health Research Institute, University of Arizona College of Medicine, Sun City, AZ 85351, USA., Benedet AL; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden., Karikari TK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden.; Department of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Triana-Baltzer G; Neuroscience Biomarkers, Janssen Research & Development, La Jolla, CA 92121, USA., Klostranec JM; Montreal Neurological Institute, Department of Diagnostic and Interventional Neuroradiology, McGill University Health Centre, 3801 Rue University, Montreal, Quebec H3A 2B4, Canada., Kolb HC; Neuroscience Biomarkers, Janssen Research & Development, La Jolla, CA 92121, USA., Zimmer ER; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, Brazil.; Department of Pharmacology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, Brazil.; Graduate Program in Biological Sciences: Pharmacology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90010-150, Brazil., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden.; Department of Neurology, Skåne University Hospital, Lund 21428, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund 22184, Sweden., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 21428, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 21428, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 41345, Sweden.; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong Science Park, Hong Kong 1512-1518, China.; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal 41390, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 41345, Sweden.; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris 75013, France.; Department of Neurology, Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, P.R. China.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 23002, P.R. China., Pascoal T; Department of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Montembeault M; Faculty of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada.; Department of Neurology and Neurosurgery, Douglas Mental Health University Institute, Verdun, Quebec H4H 1R3, Canada., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund 22184, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 21428, Sweden., Rosa-Neto P; Translational Neuroimaging Laboratory, Montreal Neurological Institute, Montreal, Quebec H3A 2B4, Canada.; Department of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Verdun, Quebec H4H 1R3, Canada.; Faculty of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada.; Department of Neurology and Neurosurgery, Douglas Mental Health University Institute, Verdun, Quebec H4H 1R3, Canada. |
| Source: | Brain : a journal of neurology [Brain] 2025 Jul 07; Vol. 148 (7), pp. 2384-2399. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2156 |
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| DOI: | 10.1093/brain/awaf033 |
