Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.

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Title: Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.
Authors: Cheng YF; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America., Kempfle JS; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chiang H; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Tani K; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Wang Q; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chen SH; Lab for Cell Dynamics, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.; National Center for Theoretical Sciences, Physics Division, Taipei, Taiwan., Lenz D; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Chen WY; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wu W; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Petrillo M; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America., Edge ASB; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, United States of America.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, Massachusetts, United States of America.; Speech and Hearing Bioscience and Technology, Harvard Medical School, Boston, Massachusetts, United States of America.; Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America.
Source: PLoS genetics [PLoS Genet] 2025 Jan 30; Vol. 21 (1), pp. e1011573. Date of Electronic Publication: 2025 Jan 30 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7404
DOI:10.1371/journal.pgen.1011573