Loss of SGK1 supports metastatic colonization in hepatocellular carcinoma by promoting resistance to T cell-mediated immunity.

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Bibliographic Details
Title: Loss of SGK1 supports metastatic colonization in hepatocellular carcinoma by promoting resistance to T cell-mediated immunity.
Authors: Zhang Z; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China., Geng C; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China., Song M; Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou, Zhejiang 311121, China., Liang H; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China., Zhou K; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China., Liu Y; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China., Wu J; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China., Huang X; Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou, Zhejiang 311121, China., Zhou J; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China., Fan J; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China., Peng DH; Dunwill Med-Tech Co., Ltd, Shanghai 201210, China. Electronic address: utsapeng@gmail.com., Zhang L; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: zhangly@shanghaitech.edu.cn., Cang Y; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: cangyong@shanghaitech.edu.cn., Sun Y; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China. Electronic address: yunfan_sun@msn.com.
Source: Journal of hepatology [J Hepatol] 2025 Aug; Vol. 83 (2), pp. 397-410. Date of Electronic Publication: 2025 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1600-0641
DOI:10.1016/j.jhep.2025.01.027