Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis.
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| Title: | Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis. |
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| Authors: | Bulcaen M; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: bulcaen2@gmail.com., Liu RB; Department of Biosystems, KU Leuven, 3001 Leuven, Belgium; Institute for Imaging, Data and Communication, University of Edinburgh, Edinburgh EH93JL, UK. Electronic address: bingnan.liu@kuleuven.be., Gryspeert K; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: kasper.gryspeert@kuleuven.be., Thierie S; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium., Ramalho AS; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium., Vermeulen F; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium; Department of Pediatrics, UZ Leuven, 3000 Leuven, Belgium., Casadevall I Solvas X; Department of Biosystems, KU Leuven, 3001 Leuven, Belgium., Carlon MS; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: marianne.carlon@kuleuven.be. |
| Source: | STAR protocols [STAR Protoc] 2025 Mar 21; Vol. 6 (1), pp. 103593. Date of Electronic Publication: 2025 Jan 31. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39893642 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bulcaen+M%22">Bulcaen M</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: bulcaen2@gmail.com.<br /><searchLink fieldCode="AU" term="%22Liu+RB%22">Liu RB</searchLink>; Department of Biosystems, KU Leuven, 3001 Leuven, Belgium; Institute for Imaging, Data and Communication, University of Edinburgh, Edinburgh EH93JL, UK. Electronic address: bingnan.liu@kuleuven.be.<br /><searchLink fieldCode="AU" term="%22Gryspeert+K%22">Gryspeert K</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: kasper.gryspeert@kuleuven.be.<br /><searchLink fieldCode="AU" term="%22Thierie+S%22">Thierie S</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ramalho+AS%22">Ramalho AS</searchLink>; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vermeulen+F%22">Vermeulen F</searchLink>; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium; Department of Pediatrics, UZ Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Casadevall+I+Solvas+X%22">Casadevall I Solvas X</searchLink>; Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Carlon+MS%22">Carlon MS</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, 3000 Leuven, Belgium. Electronic address: marianne.carlon@kuleuven.be. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101769501%22">STAR protocols</searchLink> [STAR Protoc] 2025 Mar 21; Vol. 6 (1), pp. 103593. <i>Date of Electronic Publication: </i>2025 Jan 31. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101769501 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-1667 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226661667%22">26661667 </searchLink><i>NLM ISO Abbreviation: </i>STAR Protoc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39893642 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.xpro.2024.103593 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 103593 Titles: – TitleFull: Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bulcaen M – PersonEntity: Name: NameFull: Liu RB – PersonEntity: Name: NameFull: Gryspeert K – PersonEntity: Name: NameFull: Thierie S – PersonEntity: Name: NameFull: Ramalho AS – PersonEntity: Name: NameFull: Vermeulen F – PersonEntity: Name: NameFull: Casadevall I Solvas X – PersonEntity: Name: NameFull: Carlon MS IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 03 Text: 2025 Mar 21 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2666-1667 Numbering: – Type: volume Value: 6 – Type: issue Value: 1 Titles: – TitleFull: STAR protocols Type: main |
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