Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer.
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| Title: | Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer. |
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| Authors: | Duranti C; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy., Iorio J; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy., Manganelli V; Department of Experimental Medicine, 'Sapienza' University, Rome, Italy., Bagni G; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy., Colasurdo R; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Lottini T; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy., Martinelli M; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Capitani C; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy., Boso G; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., D'Alessandro FN; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Sorice M; Department of Experimental Medicine, 'Sapienza' University, Rome, Italy., Becchetti A; Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy., Misasi R; Department of Experimental Medicine, 'Sapienza' University, Rome, Italy., Garofalo T; Department of Experimental Medicine, 'Sapienza' University, Rome, Italy., Arcangeli A; Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy. annarosa.arcangeli@unifi.it. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Feb 03; Vol. 11 (1), pp. 39. Date of Electronic Publication: 2025 Feb 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-025-02321-2 |
