Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types.
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| Title: | Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types. |
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| Authors: | Neitzel LR; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA.; Henry Ford Health + Michigan State Health Sciences, Detroit, MI, USA., Fuller DT; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Cornell J; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Rea S; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., de Aguiar Ferreira C; The Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, 48824, USA.; Department of Radiology, Michigan State University, East Lansing, MI, 48824, USA.; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 48824, USA.; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, 48824, USA., Williams CH; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA. will4277@msu.edu.; Henry Ford Health + Michigan State Health Sciences, Detroit, MI, USA. will4277@msu.edu., Hong CC; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA. hongchar@msu.edu.; Henry Ford Health + Michigan State Health Sciences, Detroit, MI, USA. hongchar@msu.edu. |
| Source: | Scientific reports [Sci Rep] 2025 Feb 03; Vol. 15 (1), pp. 4074. Date of Electronic Publication: 2025 Feb 03. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-88357-x |
