Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.

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Title: Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.
Authors: Okamoto J; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA. jokamoto@umich.edu., Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, 211166, China., Ryan B; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Chiou J; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, MA, 02139, USA., Luca F; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201, USA., Pique-Regi R; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201, USA., Im HK; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, 60637, USA., Morrison J; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA., Burant C; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA., Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, MA, 02139, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA. boehnke@umich.edu., Wen X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, 48109, USA. xwen@umich.edu.
Source: Genome biology [Genome Biol] 2025 Feb 03; Vol. 26 (1), pp. 19. Date of Electronic Publication: 2025 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-760X
DOI:10.1186/s13059-025-03480-2