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Targeted knockout and plasmid-based transfer of NRPS/PKS for improving lipopeptide iturin A synthesis.

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Title: Targeted knockout and plasmid-based transfer of NRPS/PKS for improving lipopeptide iturin A synthesis.
Authors: Hou ZJ; State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China., Lai HM; State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China., Cao CY; State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China., Xu QM; Tianjin Key Laboratory of Animal and Plant Resistance, College of Life Science, Tianjin Normal University, Binshuixi Road 393, Xiqing District, Tianjin 300387, PR China. Electronic address: qmxu0929@126.com., Cheng JS; State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Jinnan District, Tianjin 300350, PR China. Electronic address: jscheng@tju.edu.cn.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Apr; Vol. 302, pp. 140610. Date of Electronic Publication: 2025 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0003
DOI:10.1016/j.ijbiomac.2025.140610