Alterations in mucosa branched N-glycans lead to dysbiosis and downregulation of ILC3: a key driver of intestinal inflammation.

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Title: Alterations in mucosa branched N-glycans lead to dysbiosis and downregulation of ILC3: a key driver of intestinal inflammation.
Authors: Rodrigues CS; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal., Gaifem J; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal., Pereira MS; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal., Alves MF; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.; Faculty of Sciences, University of Porto, Porto, Portugal., Silva M; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal., Padrão N; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; Faculty of Medicine, University of Porto, Porto, Portugal., Cavadas B; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal., Moreira-Barbosa C; Hospital da Luz Learning Health, Luz Saúde, Lisbon, Portugal., Alves I; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal., Marcos-Pinto R; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.; Department of Gastroenterology, Centro Hospitalar do Porto, Porto, Portugal.; Centro de Investigação em Tecnologias e Serviços de Saúde, University of Porto, Porto, Portugal., Torres J; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal.; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.; Division of Gastroenterology, Hospital da Luz, Lisbon, Portugal., Lavelle A; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint-Antoine Hospital, Gastroenterology Department, Sorbonne Université, INSERM, Paris, France., Colombel JF; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sokol H; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint-Antoine Hospital, Gastroenterology Department, Sorbonne Université, INSERM, Paris, France.; INRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.; Paris Center for Microbiome Medicine (PaCeMM) FHU, Paris, France., Pinho SS; Institute for Research and Innovation in Health (i3S), Immunology, Cancer & Glycomedicine Group, University of Porto, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.; Faculty of Medicine, University of Porto, Porto, Portugal.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2461210. Date of Electronic Publication: 2025 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1949-0984
DOI:10.1080/19490976.2025.2461210