FOXO3a/miR-4259-driven LDHA expression as a key mechanism of gemcitabine sensitivity in pancreatic ductal adenocarcinoma.
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| Title: | FOXO3a/miR-4259-driven LDHA expression as a key mechanism of gemcitabine sensitivity in pancreatic ductal adenocarcinoma. |
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| Authors: | Hsu TW; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Wang WY; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Chen HA; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Surgery, Division of General Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan.; TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Wang TH; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Su CM; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Surgery, Division of General Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Liao PH; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Chen A; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Tsai KY; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Surgery, Division of General Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Kokotos G; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens, Greece., Kuo CC; Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan.; Department of Bioscience Technology, Chung Yuan Christian University, Taoyuan, Taiwan., Chiu CF; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Su YH; Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. su11066@tmu.edu.tw.; Department of Surgery, Division of General Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. su11066@tmu.edu.tw.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan. su11066@tmu.edu.tw.; TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, Taiwan. su11066@tmu.edu.tw.; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. su11066@tmu.edu.tw.; Metabolic and Weight Management Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. su11066@tmu.edu.tw. |
| Source: | Cancer & metabolism [Cancer Metab] 2025 Feb 10; Vol. 13 (1), pp. 7. Date of Electronic Publication: 2025 Feb 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101607582 Publication Model: Electronic Cited Medium: Print ISSN: 2049-3002 (Print) Linking ISSN: 20493002 NLM ISO Abbreviation: Cancer Metab Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2049-3002 |
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| DOI: | 10.1186/s40170-025-00377-3 |
