Protective antibodies against enterotoxigenic Escherichia coli are generated from heat-labile toxoid vaccination and exhibit subject- and vaccine-specific diversity.

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Title: Protective antibodies against enterotoxigenic Escherichia coli are generated from heat-labile toxoid vaccination and exhibit subject- and vaccine-specific diversity.
Authors: Maciel M Jr; Operationally Relevant Infections Department, Naval Medical Research Command, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA.; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Scott JC; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Baudier RL; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA.; Biostatistics and Design Program, Oregon Health and Sciences University, Portland, USA., Clements JD; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Laird RM; Operationally Relevant Infections Department, Naval Medical Research Command, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA.; Diarrheal Disease Research Branch, Walter Reed Army Institute of Research, Silver Spring, USA., Gutiérrez RL; Operationally Relevant Infections Department, Naval Medical Research Command, Silver Spring, MD, USA.; State University of New York Upstate Medical University, Syracuse, USA., Porter CK; Translational and Clinical Research Department, Naval Medical Research Command, Silver Spring, MD, USA., Norton EB; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA. enorton@tulane.edu.
Source: Medical microbiology and immunology [Med Microbiol Immunol] 2025 Feb 11; Vol. 214 (1), pp. 10. Date of Electronic Publication: 2025 Feb 11.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0314524 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1831 (Electronic) Linking ISSN: 03008584 NLM ISO Abbreviation: Med Microbiol Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1831
DOI:10.1007/s00430-025-00817-3