LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia.

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Title: LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia.
Authors: Boussoffara T; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Labidi I; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Trimèche M; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Chelbi I; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Dachraoui K; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Msallem N; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Abdo Saghir Abbas M; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Cherni S; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Singh KP; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Kaviraj S; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Dey R; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Varikuti S; The Ohio State University, Columbus, Ohio, USA., Gannavaram S; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., da S Pereira L; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Zhang WW; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Lypaczewski P; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Hamano S; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan., Kato H; Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan., Singh S; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Louzir H; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Nakhasi HL; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Satoskar AR; The Ohio State University, Columbus, Ohio, USA., Matlashewski G; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Zhioua E; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia. elyes.zhioua@gmail.com.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia. elyes.zhioua@gmail.com.
Source: NPJ vaccines [NPJ Vaccines] 2025 Feb 14; Vol. 10 (1), pp. 31. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2059-0105
DOI:10.1038/s41541-025-01070-8