Cerebral blood flow during simulated central hypovolaemia in people with hypertension: does vertebral artery hypoplasia matter?

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Title: Cerebral blood flow during simulated central hypovolaemia in people with hypertension: does vertebral artery hypoplasia matter?
Authors: Neumann S; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK., Rodrigues JCL; Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, UK., Simpson LL; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK., Lawton CB; Department of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust, UK., Burden D; Department of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust, UK., Kobetic MD; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.; Department of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust, UK., Adams ZH; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK., Hope K; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK., Paton JFR; Manaaki Manawa, The Centre for Heart Research, University of Auckland, Auckland, New Zealand., Blythe H; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK., Manghat N; Department of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust, UK., Barnes JN; Department of Kinesiology, Bruno Balke Biodynamics Laboratory, University of Wisconsin-Madison, Madison, WI, USA., Nightingale AK; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK., Hamilton MCH; Department of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust, UK., Hart EC; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Source: The Journal of physiology [J Physiol] 2025 Mar; Vol. 603 (6), pp. 1417-1437. Date of Electronic Publication: 2025 Feb 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-7793
DOI:10.1113/JP287786