Physiologically based pharmacokinetic model for oxcarbazepine active metabolite to predict pharmacokinetics in paediatric patients with renal impairment and adjust dosages.
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| Title: | Physiologically based pharmacokinetic model for oxcarbazepine active metabolite to predict pharmacokinetics in paediatric patients with renal impairment and adjust dosages. |
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| Authors: | Ke CJ; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Liu ST; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; The School of Pharmacy, Fujian Medical University, Fuzhou, China., Qian YD; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; The School of Pharmacy, Fujian Medical University, Fuzhou, China., You X; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Lin RF; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Lin CH; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Huang PF; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Lin WW; Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. |
| Source: | British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Jul; Vol. 91 (7), pp. 1927-1936. Date of Electronic Publication: 2025 Feb 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1365-2125 |
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| DOI: | 10.1002/bcp.70016 |
