Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms.

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Title: Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms.
Authors: Lumley SF; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK., Kent C; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Jennings D; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chai H; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Airey G; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Waddilove E; The Francis Crick Institute, London, UK., Delphin M; The Francis Crick Institute, London, UK., Trebes A; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.; Genewiz UK Ltd, Azenta Life Sciences, Stratton Court, Abingdon, UK., McNaughton AL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Mohammed KS; The Francis Crick Institute, London, UK., Wilkinson SAJ; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Wu Y; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., MacIntyre-Cockett G; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., Kimono B; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Mbonye KM; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Ojambo K; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Maponga TG; Division of Medical Virology, Stellenbosch University Faculty of Medicine and Health Sciences and National Health Laboratory Service Tygerberg Business Unit, Cape Town, South Africa., Tan CCS; The Francis Crick Institute, London, UK., de Lara C; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Martin J; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK., Campbell J; The Francis Crick Institute, London, UK., Van Schalkwyk M; Division of Infectious Diseases, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa., Goedhals D; University of the Free State, Bloemfontein, South Africa.; PathCare, Pretoria, South Africa., Newton R; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Health Sciences, University of York, York, UK., Barnes E; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Loman NJ; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Piazza P; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., Quick J; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Ansari MA; Nuffield Department of Medicine, University of Oxford, Oxford, UK. azim.ansari@ndm.ox.ac.uk., Matthews PC; The Francis Crick Institute, London, UK. philippa.matthews@crick.ac.uk.; Division of Infection and Immunity, University College London, London, UK. philippa.matthews@crick.ac.uk.; Department of Infection, University College London Hospitals, London, UK. philippa.matthews@crick.ac.uk.
Source: Scientific reports [Sci Rep] 2025 Feb 17; Vol. 15 (1), pp. 5795. Date of Electronic Publication: 2025 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-87721-1