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CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.

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Title: CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.
Authors: Moser LM; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Heim C; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Koschade SE; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany., Wendel P; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany.; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany., Bozkurt S; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany., Harenkamp S; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany., Kreyenberg H; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Merker M; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Münch C; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.; Cardio-Pulmonary Institute, Frankfurt am Main, Germany., Gradhand E; Department of Pediatric and Perinatal Pathology, Dr. Senckenberg Institute of Pathology, Goethe-University Frankfurt, Frankfurt am Main, Germany., Vogler M; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute for Experimental Pediatric Hematology and Oncology, Goethe University, Frankfurt am Main, Germany., Ullrich E; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany., Bönig H; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany.; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, United States., Klusmann JH; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Bader P; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Wels WS; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany., Rettinger E; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.
Source: Frontiers in immunology [Front Immunol] 2025 Feb 03; Vol. 16, pp. 1485817. Date of Electronic Publication: 2025 Feb 03 (Print Publication: 2025).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1485817