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CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.

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Title: CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.
Authors: Moser LM; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Heim C; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Koschade SE; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany., Wendel P; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany.; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany., Bozkurt S; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany., Harenkamp S; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany., Kreyenberg H; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Merker M; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany., Münch C; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.; Cardio-Pulmonary Institute, Frankfurt am Main, Germany., Gradhand E; Department of Pediatric and Perinatal Pathology, Dr. Senckenberg Institute of Pathology, Goethe-University Frankfurt, Frankfurt am Main, Germany., Vogler M; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute for Experimental Pediatric Hematology and Oncology, Goethe University, Frankfurt am Main, Germany., Ullrich E; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany., Bönig H; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany.; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, United States., Klusmann JH; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Bader P; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany., Wels WS; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany., Rettinger E; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.
Source: Frontiers in immunology [Front Immunol] 2025 Feb 03; Vol. 16, pp. 1485817. Date of Electronic Publication: 2025 Feb 03 (Print Publication: 2025).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Moser+LM%22">Moser LM</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Heim+C%22">Heim C</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Koschade+SE%22">Koschade SE</searchLink>; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Wendel+P%22">Wendel P</searchLink>; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany.; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Bozkurt+S%22">Bozkurt S</searchLink>; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Harenkamp+S%22">Harenkamp S</searchLink>; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Kreyenberg+H%22">Kreyenberg H</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Merker+M%22">Merker M</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Münch+C%22">Münch C</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.; Cardio-Pulmonary Institute, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Gradhand+E%22">Gradhand E</searchLink>; Department of Pediatric and Perinatal Pathology, Dr. Senckenberg Institute of Pathology, Goethe-University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Vogler+M%22">Vogler M</searchLink>; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Institute for Experimental Pediatric Hematology and Oncology, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Ullrich+E%22">Ullrich E</searchLink>; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.; Experimental Immunology & Cell Therapy, Department of Pediatrics, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bönig+H%22">Bönig H</searchLink>; Department of Cellular Therapeutics/Cell Processing, Institute for Transfusion Medicine and Immunotherapy, Goethe University, Frankfurt am Main, Germany.; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, United States.<br /><searchLink fieldCode="AU" term="%22Klusmann+JH%22">Klusmann JH</searchLink>; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bader+P%22">Bader P</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Wels+WS%22">Wels WS</searchLink>; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Rettinger+E%22">Rettinger E</searchLink>; Division for Stem Cell Transplantation and Immunology, Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; Department of Pediatrics, Goethe University Frankfurt, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.; Universitäres Centrum für Tumorerkrankungen (UCT), Frankfurt am Main, Germany.
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