K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity.
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| Title: | K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity. |
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| Authors: | Zeng Q; Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China. zengqiuming1983@csu.edu.cn.; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA. zengqiuming1983@csu.edu.cn.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA. zengqiuming1983@csu.edu.cn.; Clinical Research Center for Neuroimmune and Neuromuscular Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China. zengqiuming1983@csu.edu.cn.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China. zengqiuming1983@csu.edu.cn., Guo H; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA. guohui2022fab4@outlook.com.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA. guohui2022fab4@outlook.com., Tang N; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA., Renavikar PS; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA., Karandikar NJ; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA., Lovett-Racke AE; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA., Racke MK; Department of Neurology, The Ohio State University, Columbus, OH, 43210, USA., Yan C; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA., Tang R; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA., Sinha S; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA., Ghosh K; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA., Ryal JP; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA., Ouyang S; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA., Chen M; Genetically Engineered Mouse Modeling Core, The Ohio State University, Columbus, OH, 43210, USA., Amari F; Genetically Engineered Mouse Modeling Core, The Ohio State University, Columbus, OH, 43210, USA., Vincenzo C; Genetically Engineered Mouse Modeling Core, The Ohio State University, Columbus, OH, 43210, USA.; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, 43210, USA., Pope RM; Proteomics Facility, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Li Y; Genetically Engineered Mouse Modeling Core, The Ohio State University, Columbus, OH, 43210, USA., Yang H; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA.; Clinical Research Center for Neuroimmune and Neuromuscular Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China., Langdon WY; School of Biomedical Sciences, The University of Western Australia, Perth, Australia., Zhang J; Department of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, 52242, USA. zhanglab.uiowa@gmail.com.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA. zhanglab.uiowa@gmail.com. |
| Source: | Journal of biomedical science [J Biomed Sci] 2025 Feb 19; Vol. 32 (1), pp. 26. Date of Electronic Publication: 2025 Feb 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127 (Electronic) Linking ISSN: 10217770 NLM ISO Abbreviation: J Biomed Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1423-0127 |
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| DOI: | 10.1186/s12929-025-01120-2 |
