Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model.
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| Title: | Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model. |
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| Authors: | Mészáros M; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Faculty of Health Sciences, One Health Institute, University of Debrecen, Nagyerdei Krt. 98, 4032, Debrecen, Hungary., Phan THM; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan., Vigh JP; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary., Porkoláb G; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Kocsis A; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Szecskó A; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary., Páli EK; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Cser NM; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Polgár TF; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Theoretical Medicine Doctoral School, University of Szeged, Tisza Lajos Krt. 97, 6722, Szeged, Hungary., Kecskeméti G; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary., Walter FR; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Schwamborn JC; Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, 4365, Belvaux, Luxembourg., Janáky T; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary., Jan JS; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan., Veszelka S; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. veszelka.szilvia@brc.hu., Deli MA; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. deli.maria@brc.hu. |
| Source: | Fluids and barriers of the CNS [Fluids Barriers CNS] 2025 Feb 19; Vol. 22 (1), pp. 18. Date of Electronic Publication: 2025 Feb 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-8118 |
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| DOI: | 10.1186/s12987-025-00623-2 |
