Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model.

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Title: Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model.
Authors: Mészáros M; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Faculty of Health Sciences, One Health Institute, University of Debrecen, Nagyerdei Krt. 98, 4032, Debrecen, Hungary., Phan THM; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan., Vigh JP; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary., Porkoláb G; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Kocsis A; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Szecskó A; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary., Páli EK; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Cser NM; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Polgár TF; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Theoretical Medicine Doctoral School, University of Szeged, Tisza Lajos Krt. 97, 6722, Szeged, Hungary., Kecskeméti G; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary., Walter FR; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary., Schwamborn JC; Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, 4365, Belvaux, Luxembourg., Janáky T; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary., Jan JS; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan., Veszelka S; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. veszelka.szilvia@brc.hu., Deli MA; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. deli.maria@brc.hu.
Source: Fluids and barriers of the CNS [Fluids Barriers CNS] 2025 Feb 19; Vol. 22 (1), pp. 18. Date of Electronic Publication: 2025 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model.
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  Data: <searchLink fieldCode="AU" term="%22Mészáros+M%22">Mészáros M</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Faculty of Health Sciences, One Health Institute, University of Debrecen, Nagyerdei Krt. 98, 4032, Debrecen, Hungary.<br /><searchLink fieldCode="AU" term="%22Phan+THM%22">Phan THM</searchLink>; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Vigh+JP%22">Vigh JP</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Porkoláb+G%22">Porkoláb G</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Kocsis+A%22">Kocsis A</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Szecskó+A%22">Szecskó A</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Dugonics Tér 13, 6720, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Páli+EK%22">Páli EK</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Cser+NM%22">Cser NM</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Polgár+TF%22">Polgár TF</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.; Theoretical Medicine Doctoral School, University of Szeged, Tisza Lajos Krt. 97, 6722, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Kecskeméti+G%22">Kecskeméti G</searchLink>; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Walter+FR%22">Walter FR</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Schwamborn+JC%22">Schwamborn JC</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, 4365, Belvaux, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Janáky+T%22">Janáky T</searchLink>; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm Tér 8, 6720, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Jan+JS%22">Jan JS</searchLink>; Department of Chemical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Veszelka+S%22">Veszelka S</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. veszelka.szilvia@brc.hu.<br /><searchLink fieldCode="AU" term="%22Deli+MA%22">Deli MA</searchLink>; Institute of Biophysics, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726, Szeged, Hungary. deli.maria@brc.hu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101553157 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-8118 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220458118%22">20458118 </searchLink><i>NLM ISO Abbreviation: </i>Fluids Barriers CNS <i>Subsets: </i>MEDLINE
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