Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges.
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| Title: | Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges. |
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| Authors: | Turina P; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Petrosino M; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy., Enriquez Sandoval CA; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Novak L; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy., Pasquo A; Diagnostics and Metrology Laboratory FSN-TECFIS-DIM, ENEA CR Frascati, 00044, Frascati, Italy., Alexov E; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA., Alladin MA; Department of Computational and Data Sciences, Indian Institute of Science, Bangaluru, 560012, India., Ascher DB; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, University of Queensland, St Lucia, QLD, 4072, Australia., Babbi G; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Bakolitsa C; Department of Plant and Microbial Biology and Center for Computational Biology, University of California, Berkeley, CA, 94720, USA., Casadio R; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Cheng J; Department of Electrical Engineering and Computer Science, NextGen Precision Health Institute, University of Missouri, Columbia, MO, 65211, USA., Fariselli P; Department of Medical Sciences, University of Torino, 10126, Torino, Italy., Folkman L; Institute for Integrated and Intelligent Systems, Griffith University, Southport, QLD, 4222, Australia., Kamandula A; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Li M; School of Biology and Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou, 215123, Jiangsu, China., Li D; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Mahmud S; Department of Electrical Engineering and Computer Science, NextGen Precision Health Institute, University of Missouri, Columbia, MO, 65211, USA., Martelli PL; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Pal D; Department of Computational and Data Sciences, Indian Institute of Science, Bangaluru, 560012, India., Panday SK; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA., Pires DEV; School of Computing and Information Systems, The University of Melbourne, Melbourne, VIC, 3053, Australia., Portelli S; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, University of Queensland, St Lucia, QLD, 4072, Australia., Pucci F; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium., Rodrigues CHM; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia., Rooman M; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium., Savojardo C; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Schwersensky M; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium., Shen Y; Department of Electrical and Computer Engineering Texas, A&M University, College Station, TX, 77843, USA., Strokach AV; Department of Computer Science, University of Toronto, Toronto, ON, M5S 2E4, Canada., Sun Y; Department of Electrical and Computer Engineering Texas, A&M University, College Station, TX, 77843, USA., Woo J; 3 Billion, Seoul, South Korea., Radivojac P; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA., Brenner SE; Department of Plant and Microbial Biology and Center for Computational Biology, University of California, Berkeley, CA, 94720, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, 94720, USA.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Chiaraluce R; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy. roberta.chiaraluce@uniroma1.it., Consalvi V; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy. valerio.consalvi@uniroma1.it., Capriotti E; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy. emidio.capriotti@unibo.it.; Computational Genomics Platform, IRCCS University Hospital of Bologna, 40138, Bologna, Italy. emidio.capriotti@unibo.it. |
| Source: | Human genetics [Hum Genet] 2025 Mar; Vol. 144 (2-3), pp. 265-280. Date of Electronic Publication: 2025 Feb 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39976676 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Turina+P%22">Turina P</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Petrosino+M%22">Petrosino M</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Enriquez+Sandoval+CA%22">Enriquez Sandoval CA</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Novak+L%22">Novak L</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pasquo+A%22">Pasquo A</searchLink>; Diagnostics and Metrology Laboratory FSN-TECFIS-DIM, ENEA CR Frascati, 00044, Frascati, Italy.<br /><searchLink fieldCode="AU" term="%22Alexov+E%22">Alexov E</searchLink>; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA.<br /><searchLink fieldCode="AU" term="%22Alladin+MA%22">Alladin MA</searchLink>; Department of Computational and Data Sciences, Indian Institute of Science, Bangaluru, 560012, India.<br /><searchLink fieldCode="AU" term="%22Ascher+DB%22">Ascher DB</searchLink>; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, University of Queensland, St Lucia, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Babbi+G%22">Babbi G</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Bakolitsa+C%22">Bakolitsa C</searchLink>; Department of Plant and Microbial Biology and Center for Computational Biology, University of California, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Casadio+R%22">Casadio R</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Cheng+J%22">Cheng J</searchLink>; Department of Electrical Engineering and Computer Science, NextGen Precision Health Institute, University of Missouri, Columbia, MO, 65211, USA.<br /><searchLink fieldCode="AU" term="%22Fariselli+P%22">Fariselli P</searchLink>; Department of Medical Sciences, University of Torino, 10126, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Folkman+L%22">Folkman L</searchLink>; Institute for Integrated and Intelligent Systems, Griffith University, Southport, QLD, 4222, Australia.<br /><searchLink fieldCode="AU" term="%22Kamandula+A%22">Kamandula A</searchLink>; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Katsonis+P%22">Katsonis P</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; School of Biology and Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou, 215123, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Lichtarge+O%22">Lichtarge O</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Mahmud+S%22">Mahmud S</searchLink>; Department of Electrical Engineering and Computer Science, NextGen Precision Health Institute, University of Missouri, Columbia, MO, 65211, USA.<br /><searchLink fieldCode="AU" term="%22Martelli+PL%22">Martelli PL</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Pal+D%22">Pal D</searchLink>; Department of Computational and Data Sciences, Indian Institute of Science, Bangaluru, 560012, India.<br /><searchLink fieldCode="AU" term="%22Panday+SK%22">Panday SK</searchLink>; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA.<br /><searchLink fieldCode="AU" term="%22Pires+DEV%22">Pires DEV</searchLink>; School of Computing and Information Systems, The University of Melbourne, Melbourne, VIC, 3053, Australia.<br /><searchLink fieldCode="AU" term="%22Portelli+S%22">Portelli S</searchLink>; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, University of Queensland, St Lucia, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Pucci+F%22">Pucci F</searchLink>; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rodrigues+CHM%22">Rodrigues CHM</searchLink>; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Rooman+M%22">Rooman M</searchLink>; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Savojardo+C%22">Savojardo C</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Schwersensky+M%22">Schwersensky M</searchLink>; Computational Biology and Bioinformatics, Université Libre de Bruxelles, 1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Department of Electrical and Computer Engineering Texas, A&M University, College Station, TX, 77843, USA.<br /><searchLink fieldCode="AU" term="%22Strokach+AV%22">Strokach AV</searchLink>; Department of Computer Science, University of Toronto, Toronto, ON, M5S 2E4, Canada.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Electrical and Computer Engineering Texas, A&M University, College Station, TX, 77843, USA.<br /><searchLink fieldCode="AU" term="%22Woo+J%22">Woo J</searchLink>; 3 Billion, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Radivojac+P%22">Radivojac P</searchLink>; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Brenner+SE%22">Brenner SE</searchLink>; Department of Plant and Microbial Biology and Center for Computational Biology, University of California, Berkeley, CA, 94720, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, 94720, USA.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Chiaraluce+R%22">Chiaraluce R</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy. roberta.chiaraluce@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Consalvi+V%22">Consalvi V</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Roma, 00185, Rome, Italy. valerio.consalvi@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Capriotti+E%22">Capriotti E</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy. emidio.capriotti@unibo.it.; Computational Genomics Platform, IRCCS University Hospital of Bologna, 40138, Bologna, Italy. emidio.capriotti@unibo.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227613873%22">Human genetics</searchLink> [Hum Genet] 2025 Mar; Vol. 144 (2-3), pp. 265-280. <i>Date of Electronic Publication: </i>2025 Feb 20. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7613873 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203406717%22">03406717 </searchLink><i>NLM ISO Abbreviation: </i>Hum Genet <i>Subsets: </i>MEDLINE |
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