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YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs.

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Title: YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs.
Authors: Pereira MF; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Finazzi V; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Rizzuti L; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Aprile D; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Aiello V; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Mollica L; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Riva M; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Soriani C; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy., Dossena F; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Shyti R; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Castaldi D; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Tenderini E; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy., Carminho-Rodrigues MT; Department of Genetics, University of Geneva & University Hospitals of Geneva, Geneva, Switzerland., Bally JF; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital & University of Lausanne, Lausanne, Switzerland., de Vries BBA; Radboud University UMC, Nijmegen, The Netherlands., Gabriele M; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Cambridge, MA, 02139, USA., Vitriolo A; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy., Testa G; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy. giuseppe.testa@fht.org.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy. giuseppe.testa@fht.org.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy. giuseppe.testa@fht.org.
Source: Molecular psychiatry [Mol Psychiatry] 2025 Aug; Vol. 30 (8), pp. 3413-3429. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs.
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  Data: <searchLink fieldCode="AU" term="%22Pereira+MF%22">Pereira MF</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Finazzi+V%22">Finazzi V</searchLink>; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzuti+L%22">Rizzuti L</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Aprile+D%22">Aprile D</searchLink>; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Aiello+V%22">Aiello V</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mollica+L%22">Mollica L</searchLink>; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Riva+M%22">Riva M</searchLink>; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Soriani+C%22">Soriani C</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dossena+F%22">Dossena F</searchLink>; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Shyti+R%22">Shyti R</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Castaldi+D%22">Castaldi D</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tenderini+E%22">Tenderini E</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carminho-Rodrigues+MT%22">Carminho-Rodrigues MT</searchLink>; Department of Genetics, University of Geneva & University Hospitals of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bally+JF%22">Bally JF</searchLink>; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital & University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22de+Vries+BBA%22">de Vries BBA</searchLink>; Radboud University UMC, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gabriele+M%22">Gabriele M</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Vitriolo+A%22">Vitriolo A</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Testa+G%22">Testa G</searchLink>; Department of Experimental Oncology, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy. giuseppe.testa@fht.org.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20122, Milan, Italy. giuseppe.testa@fht.org.; Human Technopole, Viale Rita Levi-Montalcini 1, 20157, Milan, Italy. giuseppe.testa@fht.org.
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