Combined tumor-associated microbiome and immune gene expression profiling predict response to neoadjuvant chemo-radiotherapy in locally advanced rectal cancer.
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| Title: | Combined tumor-associated microbiome and immune gene expression profiling predict response to neoadjuvant chemo-radiotherapy in locally advanced rectal cancer. |
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| Authors: | Roesel R; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Strati F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy., Basso C; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Epistolio S; Laboratory of Molecular Pathology, Institute of Pathology, Locarno, Switzerland., Spina P; Laboratory of Molecular Pathology, Institute of Pathology, Locarno, Switzerland., Djordjevic J; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Sorrenti E; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Villa M; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Cianfarani A; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Mongelli F; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Galafassi J; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Popeskou SG; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Facciotti F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy., Caprera C; Division of Hematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy., Melle F; Division of Hematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy., Majno-Hurst PE; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Franzetti-Pellanda A; Service of Radiotherapy, Gruppo Ospedaliero Moncucco, Clinica Moncucco, Lugano, Switzerland., De Dosso S; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.; Department of Medical Oncology, Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Bonfiglio F; Department of Molecular Medicine and Medical Biotechnology, University of Naples, Naples, Italy.; CEINGE Advanced Biotechnology Franco Salvatore, Università degli Studi di Napoli Federico II, Naples, Italy., Frattini M; Laboratory of Molecular Pathology, Institute of Pathology, Locarno, Switzerland., Christoforidis D; Department of Surgery, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.; Department of Visceral Surgery, CHUV, University of Lausanne, Lausanne, Switzerland., Iezzi G; Laboratory for Translational Surgical Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland. |
| Source: | Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2465015. Date of Electronic Publication: 2025 Feb 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2162-402X |
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| DOI: | 10.1080/2162402X.2025.2465015 |
