Pharmacokinetics of major indigo naturalis indole alkaloids in humans and their association with systemic aryl hydrocarbon receptor activity.

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Title: Pharmacokinetics of major indigo naturalis indole alkaloids in humans and their association with systemic aryl hydrocarbon receptor activity.
Authors: Tang JS; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: jtang@malaghan.org.nz., Cait A; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., O'Sullivan D; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Waugh C; Cawthron Institute, Nelson, New Zealand., van Ginkel R; Cawthron Institute, Nelson, New Zealand., Passfield E; Cawthron Institute, Nelson, New Zealand., Gell K; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Li Y; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Faulkner S; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Herst PM; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; University of Otago, Wellington, New Zealand., Gasser O; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: ogasser@malaghan.org.nz.
Source: Biochemical pharmacology [Biochem Pharmacol] 2025 May; Vol. 235, pp. 116805. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2968
DOI:10.1016/j.bcp.2025.116805