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Pharmacokinetics of major indigo naturalis indole alkaloids in humans and their association with systemic aryl hydrocarbon receptor activity.

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Title: Pharmacokinetics of major indigo naturalis indole alkaloids in humans and their association with systemic aryl hydrocarbon receptor activity.
Authors: Tang JS; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: jtang@malaghan.org.nz., Cait A; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., O'Sullivan D; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Waugh C; Cawthron Institute, Nelson, New Zealand., van Ginkel R; Cawthron Institute, Nelson, New Zealand., Passfield E; Cawthron Institute, Nelson, New Zealand., Gell K; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Li Y; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Faulkner S; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Herst PM; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; University of Otago, Wellington, New Zealand., Gasser O; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: ogasser@malaghan.org.nz.
Source: Biochemical pharmacology [Biochem Pharmacol] 2025 May; Vol. 235, pp. 116805. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacokinetics of major indigo naturalis indole alkaloids in humans and their association with systemic aryl hydrocarbon receptor activity.
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  Data: <searchLink fieldCode="AU" term="%22Tang+JS%22">Tang JS</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: jtang@malaghan.org.nz.<br /><searchLink fieldCode="AU" term="%22Cait+A%22">Cait A</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22O'Sullivan+D%22">O'Sullivan D</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Waugh+C%22">Waugh C</searchLink>; Cawthron Institute, Nelson, New Zealand.<br /><searchLink fieldCode="AU" term="%22van+Ginkel+R%22">van Ginkel R</searchLink>; Cawthron Institute, Nelson, New Zealand.<br /><searchLink fieldCode="AU" term="%22Passfield+E%22">Passfield E</searchLink>; Cawthron Institute, Nelson, New Zealand.<br /><searchLink fieldCode="AU" term="%22Gell+K%22">Gell K</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Faulkner+S%22">Faulkner S</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Herst+PM%22">Herst PM</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; University of Otago, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Gasser+O%22">Gasser O</searchLink>; Malaghan Institute of Medical Research, PO Box 7060, Wellington 6242, New Zealand; High-Value Nutrition National Science Challenge, Auckland, New Zealand. Electronic address: ogasser@malaghan.org.nz.
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  Data: <searchLink fieldCode="JN" term="%220101032%22">Biochemical pharmacology</searchLink> [Biochem Pharmacol] 2025 May; Vol. 235, pp. 116805. <i>Date of Electronic Publication: </i>2025 Feb 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0101032 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2968 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200062952%22">00062952 </searchLink><i>NLM ISO Abbreviation: </i>Biochem Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2025 May
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