Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2.
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| Title: | Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2. |
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| Authors: | Schmidt H; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhang M; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chakarov D; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Bansal V; Center for Statistics and Machine Learning, Princeton University, Princeton, NJ, USA., Mourelatos H; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell/Rockefeller/Memorial Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Sánchez-Rivera FJ; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Present address: David H. Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ventura A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. venturaa@mskcc.org., Leslie CS; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lesliec@mskcc.org., Pritykin Y; Department of Computer Science, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. pritykin@princeton.edu.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu. |
| Source: | Genome biology [Genome Biol] 2025 Feb 26; Vol. 26 (1), pp. 41. Date of Electronic Publication: 2025 Feb 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1474-760X |
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| DOI: | 10.1186/s13059-025-03488-8 |
