Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2.

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Title: Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2.
Authors: Schmidt H; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhang M; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chakarov D; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Bansal V; Center for Statistics and Machine Learning, Princeton University, Princeton, NJ, USA., Mourelatos H; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell/Rockefeller/Memorial Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Sánchez-Rivera FJ; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Present address: David H. Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ventura A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. venturaa@mskcc.org., Leslie CS; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lesliec@mskcc.org., Pritykin Y; Department of Computer Science, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. pritykin@princeton.edu.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.
Source: Genome biology [Genome Biol] 2025 Feb 26; Vol. 26 (1), pp. 41. Date of Electronic Publication: 2025 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
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  Data: Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2.
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  Data: <searchLink fieldCode="AU" term="%22Schmidt+H%22">Schmidt H</searchLink>; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chakarov+D%22">Chakarov D</searchLink>; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Bansal+V%22">Bansal V</searchLink>; Center for Statistics and Machine Learning, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Mourelatos+H%22">Mourelatos H</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell/Rockefeller/Memorial Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sánchez-Rivera+FJ%22">Sánchez-Rivera FJ</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Present address: David H. Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lowe+SW%22">Lowe SW</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ventura+A%22">Ventura A</searchLink>; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. venturaa@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Leslie+CS%22">Leslie CS</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lesliec@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Pritykin+Y%22">Pritykin Y</searchLink>; Department of Computer Science, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. pritykin@princeton.edu.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2025 Feb 26; Vol. 26 (1), pp. 41. <i>Date of Electronic Publication: </i>2025 Feb 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100960660 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-760X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214747596%22">14747596 </searchLink><i>NLM ISO Abbreviation: </i>Genome Biol <i>Subsets: </i>MEDLINE
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