Neoadjuvant therapy-induced remodeling of tumor immune microenvironment in pancreatic ductal adenocarcinoma: a spatial and digital pathology analysis.

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Title: Neoadjuvant therapy-induced remodeling of tumor immune microenvironment in pancreatic ductal adenocarcinoma: a spatial and digital pathology analysis.
Authors: Li D; Department of Biostatistics and Data Science, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Liu Y; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA., Lan R; Department of Biostatistics and Data Science, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Pillarisetty VG; Department of Surgery, University of Washington School of Medicine, Seattle, WA, USA., Zhang X; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. xiaofei.zhang@nyulangone.org.; Department of Pathology and Laboratory Medicine, New York University Grossman Long Island School of Medicine, Long Island, NY, USA. xiaofei.zhang@nyulangone.org., Liu YZ; Department of Biostatistics and Data Science, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA. yliu8@tulane.edu.
Source: Virchows Archiv : an international journal of pathology [Virchows Arch] 2026 Feb; Vol. 488 (2), pp. 277-290. Date of Electronic Publication: 2025 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9423843 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2307 (Electronic) Linking ISSN: 09456317 NLM ISO Abbreviation: Virchows Arch Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-2307
DOI:10.1007/s00428-025-04056-y