Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection.
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| Title: | Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection. |
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| Authors: | Klawon DEJ; Department of Pathology, University of Chicago, Chicago, IL, USA., Pagane N; The Ragon Institute of Mass General, MIT and Harvard, Cambridge, MA, USA.; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Walker MT; Department of Pathology, University of Chicago, Chicago, IL, USA., Ganci NK; Department of Pathology, University of Chicago, Chicago, IL, USA., Miller CH; Department of Pathology, University of Chicago, Chicago, IL, USA.; Interdisciplinary Scientist Training Program, University of Chicago, Chicago, IL, USA., Gai E; The Ragon Institute of Mass General, MIT and Harvard, Cambridge, MA, USA.; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Rodriguez DM; Department of Pathology, University of Chicago, Chicago, IL, USA.; Interdisciplinary Scientist Training Program, University of Chicago, Chicago, IL, USA., Ryan-Payseur BK; Department of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA., Duncombe RK; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA., Adams EJ; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA., Maienschein-Cline M; Research Informatics Core, Research Resources Center, University of Illinois Chicago, Chicago, IL, USA., Freitag NE; Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA., Germain RN; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wong HS; The Ragon Institute of Mass General, MIT and Harvard, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Savage PA; Department of Pathology, University of Chicago, Chicago, IL, USA. |
| Source: | Science (New York, N.Y.) [Science] 2025 Mar 21; Vol. 387 (6740), pp. eadk3248. Date of Electronic Publication: 2025 Mar 21. |
| Publication Type: | Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adk3248 |
