Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-Terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity.

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Title: Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-Terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity.
Authors: Neuville M; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France.; IMMUPHARMA BIOTECH SAS, 15 rue de Bruxelles, 75009, Paris, France., Bourgeais M; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France.; Univ. Bordeaux, INSERM, BRIC, U 1312, F-33000, Bordeaux, France., Buratto J; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Saragaglia C; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Li B; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Galeano-Otero I; Univ. Bordeaux, INSERM, BRIC, U 1312, F-33000, Bordeaux, France., Mauran L; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France.; IMMUPHARMA BIOTECH SAS, 15 rue de Bruxelles, 75009, Paris, France., Varajao L; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Goudreau SR; IMMUPHARMA BIOTECH SAS, 15 rue de Bruxelles, 75009, Paris, France., Kauffmann B; Univ. Bordeaux, CNRS, INSERM, IECB, UAR3033, US001, F-33600, Pessac, France., Thinon E; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Pasco M; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France., Khatib AM; Univ. Bordeaux, INSERM, BRIC, U 1312, F-33000, Bordeaux, France., Guichard G; Univ. Bordeaux, CNRS, Bordeaux INP, CBMN, UMR 5248, IECB, 2 rue Robert Escarpit, F-33600, Pessac, France.
Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2025 Apr 01; Vol. 31 (19), pp. e202403330. Date of Electronic Publication: 2025 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1521-3765
DOI:10.1002/chem.202403330