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Corticosteroid and antimicrobial therapy in macrolide-resistant pneumococcal pneumonia porcine model.

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Title: Corticosteroid and antimicrobial therapy in macrolide-resistant pneumococcal pneumonia porcine model.
Authors: Motos A; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; University of Nantes, Nantes, France., Yang M; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Infectious Diseases, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China., Battaglini D; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Yang H; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China., Meli A; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Internal Medicine Department, Respiratory Unit and Adult Cystic Fibrosis Center, and Department of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy., Bobi J; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, 3015, Rotterdam, The Netherlands., Cabrera R; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Tanzella G; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Vargas CR; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Arrieta M; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Llonch B; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Rovira-Ribalta N; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Barbeta E; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; Surgical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain., di Giannatale P; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Department of Anesthesiology, Critical Care Medicine and Emergency, SS. Annunziata Hospital, Chieti, Italy., Nogas S; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Fernández-Barat L; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain., Rigol M; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Kiarostami K; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Martín-Loeches I; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St. James's Hospital, James's Street, Dublin, D08 NHY1, Ireland., Vila J; University of Barcelona, Barcelona, Spain.; ISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Microbiology, Centre for Biomedical Diagnosis, Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica En Red- Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Martinez D; University of Barcelona, Barcelona, Spain.; Department of Pathology, Hospital Clinic, Barcelona, Spain., Bassi GL; Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, Australia.; University of Queensland, St Lucia, QLD, Australia.; Queensland University of Technology, Kelving Grove, QLD, Australia.; The Wesley Medical Research, Auchenflower, QLD, Australia., Torres A; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain. atorres@ub.edu.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain. atorres@ub.edu.; University of Barcelona, Barcelona, Spain. atorres@ub.edu.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain. atorres@ub.edu.; Servei de Pneumologia I Al•Lèrgia Respiratoria, Hospital Clínic, Calle Villarroel 170, Esc 6/8 Planta 2, 08036, Barcelona, Spain. atorres@ub.edu.
Source: Intensive care medicine experimental [Intensive Care Med Exp] 2025 Feb 27; Vol. 13 (1), pp. 27. Date of Electronic Publication: 2025 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101645149 Publication Model: Electronic Cited Medium: Print ISSN: 2197-425X (Print) Linking ISSN: 2197425X NLM ISO Abbreviation: Intensive Care Med Exp Subsets: PubMed not MEDLINE
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  Data: Corticosteroid and antimicrobial therapy in macrolide-resistant pneumococcal pneumonia porcine model.
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  Data: <searchLink fieldCode="AU" term="%22Motos+A%22">Motos A</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; University of Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Infectious Diseases, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Battaglini+D%22">Battaglini D</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Meli+A%22">Meli A</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Internal Medicine Department, Respiratory Unit and Adult Cystic Fibrosis Center, and Department of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bobi+J%22">Bobi J</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, 3015, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cabrera+R%22">Cabrera R</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tanzella+G%22">Tanzella G</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Vargas+CR%22">Vargas CR</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Arrieta+M%22">Arrieta M</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Llonch+B%22">Llonch B</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rovira-Ribalta+N%22">Rovira-Ribalta N</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Barbeta+E%22">Barbeta E</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; Surgical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22di+Giannatale+P%22">di Giannatale P</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Department of Anesthesiology, Critical Care Medicine and Emergency, SS. Annunziata Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Nogas+S%22">Nogas S</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Fernández-Barat+L%22">Fernández-Barat L</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rigol+M%22">Rigol M</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Kiarostami+K%22">Kiarostami K</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martín-Loeches+I%22">Martín-Loeches I</searchLink>; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain.; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St. James's Hospital, James's Street, Dublin, D08 NHY1, Ireland.<br /><searchLink fieldCode="AU" term="%22Vila+J%22">Vila J</searchLink>; University of Barcelona, Barcelona, Spain.; ISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Microbiology, Centre for Biomedical Diagnosis, Hospital Clínic, Barcelona, Spain.; Centro de Investigación Biomédica En Red- Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez+D%22">Martinez D</searchLink>; University of Barcelona, Barcelona, Spain.; Department of Pathology, Hospital Clinic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bassi+GL%22">Bassi GL</searchLink>; Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, Australia.; University of Queensland, St Lucia, QLD, Australia.; Queensland University of Technology, Kelving Grove, QLD, Australia.; The Wesley Medical Research, Auchenflower, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Torres+A%22">Torres A</searchLink>; Pneumology Department, Hospital Clínic, Thorax Institute, Barcelona, Spain. atorres@ub.edu.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain. atorres@ub.edu.; University of Barcelona, Barcelona, Spain. atorres@ub.edu.; Centro de Investigación Biomedica En Red- Enfermedades Respiratorias (CIBERES), Barcelona, Spain. atorres@ub.edu.; Servei de Pneumologia I Al•Lèrgia Respiratoria, Hospital Clínic, Calle Villarroel 170, Esc 6/8 Planta 2, 08036, Barcelona, Spain. atorres@ub.edu.
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