Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased.

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Title: Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased.
Authors: Polysopoulos C; Statistics Group, Swiss Clinical Quality Management (SCQM) Foundation, Aargauerstrasse 250, Zurich, 8048, Switzerland., Georgiadis S; Copenhagen Centre for Arthritis Research (COPECARE), Centre for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark., Ørnbjerg LM; Copenhagen Centre for Arthritis Research (COPECARE), Centre for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark., Scherer A; Statistics Group, Swiss Clinical Quality Management (SCQM) Foundation, Aargauerstrasse 250, Zurich, 8048, Switzerland., Di Giuseppe D; Department of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden., Hetland ML; Copenhagen Centre for Arthritis Research (COPECARE) and the DANBIO Registry, Centre for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark., Nissen MJ; Department of Rheumatology, Geneva University Hospital, Geneva, Switzerland., Jones GT; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK., Glintborg B; Copenhagen Centre for Arthritis Research (COPECARE) and the DANBIO Registry, Centre for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark., Loft AG; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark., Wallman JK; Department of Clinical Sciences Lund, Rheumatology, Skåne University Hospital, Lund University, Lund, Sweden., Pavelka K; Institute of Rheumatology, Prague, Czech Republic., Závada J; Institute of Rheumatology, Prague, Czech Republic., Yazici A; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kocaeli University, Kocaeli, Turkey., Santos MJ; Sociedade Portuguesa de Reumatologia, Reuma.Pt, Lisbon, Portugal., Ciurea A; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Möller B; Department Rheumatology and Immunology, Inselspital - University Hospital Bern, Bern, Switzerland., Michelsen B; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Mielnik P; Section for Rheumatology, Department for Neurology, Rheumatology and Physical Medicine, Helse Førde, Førde, Norway., Huhtakangas J; Department of Rheumatology, Kuopio University Hospital, Kuopio, Finland., Relas H; Rheumatology, Inflammation Center, Helsinki University Hospital and University of Helsink, Helsinki, Finland., Pirkmajer KP; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Rotar Z; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., MacDonald R; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK., Gudbjornsson B; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Centre for Rheumatology Research, Landspitali University Hospital, Reykjavik, Iceland., van der Horst-Bruinsma I; Rheumatology, Radboud University Medical Centre, Nijmegen, The Netherlands., van de Sande M; Amsterdam UMC, Department of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam Institute for Infection & Immunity, University of Amsterdam, Amsterdam, The Netherlands., Riek M; Statistics Group, Swiss Clinical Quality Management (SCQM) Foundation, Aargauerstrasse 250, Zurich, 8048, Switzerland. myriam.riek@scqm.ch.
Source: BMC medical research methodology [BMC Med Res Methodol] 2025 Feb 28; Vol. 25 (1), pp. 55. Date of Electronic Publication: 2025 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968545 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2288 (Electronic) Linking ISSN: 14712288 NLM ISO Abbreviation: BMC Med Res Methodol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1471-2288
DOI:10.1186/s12874-025-02515-3