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Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics.

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Title: Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics.
Authors: Mykkänen AJH; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Tarkiainen EK; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Taskinen S; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Neuvonen M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Paile-Hyvärinen M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Lilius TO; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Tapaninen T; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Backman JT; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Tornio A; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland., Niemi M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Jun; Vol. 117 (6), pp. 1763-1774. Date of Electronic Publication: 2025 Mar 03.
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mykkänen+AJH%22">Mykkänen AJH</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tarkiainen+EK%22">Tarkiainen EK</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Taskinen+S%22">Taskinen S</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Neuvonen+M%22">Neuvonen M</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Paile-Hyvärinen+M%22">Paile-Hyvärinen M</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lilius+TO%22">Lilius TO</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tapaninen+T%22">Tapaninen T</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Backman+JT%22">Backman JT</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tornio+A%22">Tornio A</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Niemi+M%22">Niemi M</searchLink>; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.
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