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Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.

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Title: Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.
Authors: Costanza M; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany., Giordano C, von Brünneck AC, Zhao J, Makky A, Vinh K, Montes-Mojarro IA, Reisinger F, Forchhammer S; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Witalisz-Siepracka A, Edtmayer S, Stoiber D, Yin G, Horst D; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Fischer A, Siebert R, Nicolay JP; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Yin M; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Janz M; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany., Fend F; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Becker JC; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Schürch CM; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Kenner L, Assaf C, Merkel O, Mathas S; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Source: The British journal of dermatology [Br J Dermatol] 2025 Apr 28; Vol. 192 (5), pp. 883-895.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.
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  Data: <searchLink fieldCode="AU" term="%22Costanza+M%22">Costanza M</searchLink>; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Giordano+C%22">Giordano C</searchLink><br /><searchLink fieldCode="AU" term="%22von+Brünneck+AC%22">von Brünneck AC</searchLink><br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink><br /><searchLink fieldCode="AU" term="%22Makky+A%22">Makky A</searchLink><br /><searchLink fieldCode="AU" term="%22Vinh+K%22">Vinh K</searchLink><br /><searchLink fieldCode="AU" term="%22Montes-Mojarro+IA%22">Montes-Mojarro IA</searchLink><br /><searchLink fieldCode="AU" term="%22Reisinger+F%22">Reisinger F</searchLink><br /><searchLink fieldCode="AU" term="%22Forchhammer+S%22">Forchhammer S</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Witalisz-Siepracka+A%22">Witalisz-Siepracka A</searchLink><br /><searchLink fieldCode="AU" term="%22Edtmayer+S%22">Edtmayer S</searchLink><br /><searchLink fieldCode="AU" term="%22Stoiber+D%22">Stoiber D</searchLink><br /><searchLink fieldCode="AU" term="%22Yin+G%22">Yin G</searchLink><br /><searchLink fieldCode="AU" term="%22Horst+D%22">Horst D</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+A%22">Fischer A</searchLink><br /><searchLink fieldCode="AU" term="%22Siebert+R%22">Siebert R</searchLink><br /><searchLink fieldCode="AU" term="%22Nicolay+JP%22">Nicolay JP</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Yin+M%22">Yin M</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Janz+M%22">Janz M</searchLink>; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Fend+F%22">Fend F</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+JC%22">Becker JC</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schürch+CM%22">Schürch CM</searchLink>; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kenner+L%22">Kenner L</searchLink><br /><searchLink fieldCode="AU" term="%22Assaf+C%22">Assaf C</searchLink><br /><searchLink fieldCode="AU" term="%22Merkel+O%22">Merkel O</searchLink><br /><searchLink fieldCode="AU" term="%22Mathas+S%22">Mathas S</searchLink>; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Biology of Malignant Lymphomas, Berlin, Germany.; Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany.; Experimental and Clinical Research Center (ECRC), a joint cooperation between Charité and MDC, Berlin, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
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