Comparison of the in vivo efficacy and resistance development potential between cefiderocol and ceftolozane/tazobactam human simulated exposures against Pseudomonas aeruginosa in 72-hour murine thigh infection model.

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Title: Comparison of the in vivo efficacy and resistance development potential between cefiderocol and ceftolozane/tazobactam human simulated exposures against Pseudomonas aeruginosa in 72-hour murine thigh infection model.
Authors: Fouad A; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA., Nicolau SE; mRNA Center of Excellence, Sanofi Pasteur, Waltham, MA, USA., Tamma PD; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Simner PJ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nicolau DP; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.; Division of Infectious Diseases, Hartford Hospital, Hartford, CT, USA., Gill CM; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.
Source: Infectious diseases (London, England) [Infect Dis (Lond)] 2025 Jul; Vol. 57 (7), pp. 658-668. Date of Electronic Publication: 2025 Mar 05.
Publication Type: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101650235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2374-4243 (Electronic) Linking ISSN: 23744243 NLM ISO Abbreviation: Infect Dis (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparison of the in vivo efficacy and resistance development potential between cefiderocol and ceftolozane/tazobactam human simulated exposures against Pseudomonas aeruginosa in 72-hour murine thigh infection model.
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  Data: <searchLink fieldCode="AU" term="%22Fouad+A%22">Fouad A</searchLink>; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.<br /><searchLink fieldCode="AU" term="%22Nicolau+SE%22">Nicolau SE</searchLink>; mRNA Center of Excellence, Sanofi Pasteur, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tamma+PD%22">Tamma PD</searchLink>; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Simner+PJ%22">Simner PJ</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nicolau+DP%22">Nicolau DP</searchLink>; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.; Division of Infectious Diseases, Hartford Hospital, Hartford, CT, USA.<br /><searchLink fieldCode="AU" term="%22Gill+CM%22">Gill CM</searchLink>; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.
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  Data: <searchLink fieldCode="JN" term="%22101650235%22">Infectious diseases (London, England)</searchLink> [Infect Dis (Lond)] 2025 Jul; Vol. 57 (7), pp. 658-668. <i>Date of Electronic Publication: </i>2025 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101650235 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2374-4243 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223744243%22">23744243 </searchLink><i>NLM ISO Abbreviation: </i>Infect Dis (Lond) <i>Subsets: </i>MEDLINE
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        Value: 10.1080/23744235.2025.2471822
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