Chanoclavine synthase operates by an NADPH-independent superoxide mechanism.
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| Title: | Chanoclavine synthase operates by an NADPH-independent superoxide mechanism. |
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| Authors: | Chen CC; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China.; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Yu ZP; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; MOE Key Laboratory of Marine Drugs and Key Laboratory of Evolution and Marine Biodiversity, School of Medicine and Pharmacy, Institute of Evolution & Marine Biodiversity, Ocean University of China, Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao, People's Republic of China., Liu Z; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Yao Y; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China., Hagedoorn PL; Biocatalysis, Department of Biotechnology, Delft University of Technology, Delft, The Netherlands., Schmitz RA; Biocatalysis, Department of Biotechnology, Delft University of Technology, Delft, The Netherlands., Yang L; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Yu L; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China., Liu A; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.; High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People's Republic of China., Sheng X; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Su H; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Ma Y; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China., Wang T; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Huang JW; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Zhang L; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Yan J; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Bao J; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Cui C; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China., Li X; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Shen P; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Zhang W; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China.; MOE Key Laboratory of Marine Drugs and Key Laboratory of Evolution and Marine Biodiversity, School of Medicine and Pharmacy, Institute of Evolution & Marine Biodiversity, Ocean University of China, Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao, People's Republic of China., Min J; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China., Wang CY; MOE Key Laboratory of Marine Drugs and Key Laboratory of Evolution and Marine Biodiversity, School of Medicine and Pharmacy, Institute of Evolution & Marine Biodiversity, Ocean University of China, Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao, People's Republic of China., Guo RT; Zhejiang Key Laboratory of Medical Epigenetics, Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, People's Republic of China. guoreyting@hznu.edu.cn.; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, People's Republic of China. guoreyting@hznu.edu.cn., Gao SS; State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, People's Republic of China. gaoss@tib.cas.cn.; National Center of Technology Innovation for Synthetic Biology, Tianjin, People's Republic of China. gaoss@tib.cas.cn. |
| Source: | Nature [Nature] 2025 Apr; Vol. 640 (8059), pp. 840-846. Date of Electronic Publication: 2025 Mar 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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