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Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts.

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Title: Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts.
Authors: Emrani S; Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA., Koutures A; Boston University, Boston, MA, USA., Tripodis Y; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Uretsky M; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA., Abdolmohammadi B; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA., Nowinski C; Concussion Legacy Foundation, Boston, MA, USA., Daneshvar DH; Department of Rehabilitation Medicine, Harvard Medical School, Boston, MA, USA., Dwyer B; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Braintree Rehabilitation Hospital, Braintree, MA, USA., Katz DI; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Braintree Rehabilitation Hospital, Braintree, MA, USA., Goldstein LE; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Departments of Biomedical, Electrical & Computer Engineering, Boston University College of Engineering, Boston, MA, USA., Cantu RC; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Concussion Legacy Foundation, Boston, MA, USA.; Department of Neurosurgery, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Neurosurgery, Emerson Hospital, Concord, MA, USA., Martin BM; Biostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, MA, USA., Palmisano JN; Biostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, MA, USA., Dams-O'Connor K; Department of Rehabilitation and Human Performance, Brain Injury Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Crary JF; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Stern RA; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurosurgery, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Mez J; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA., Alvarez VE; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; U.S. Department of Veteran Affairs, VA Boston Healthcare System, Boston, MA, USA.; Department of Veterans Affairs Medical Center, Bedford, MA, USA., Huber BR; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; U.S. Department of Veteran Affairs, VA Boston Healthcare System, Boston, MA, USA.; Department of Veterans Affairs Medical Center, Bedford, MA, USA., McKee AC; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; U.S. Department of Veteran Affairs, VA Boston Healthcare System, Boston, MA, USA.; Department of Veterans Affairs Medical Center, Bedford, MA, USA., Stein TD; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; U.S. Department of Veteran Affairs, VA Boston Healthcare System, Boston, MA, USA.; Department of Veterans Affairs Medical Center, Bedford, MA, USA., Alosco ML; Alzheimer's Disease Research Center and Chronic Traumatic Encephalopathy Center, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA. malosco@bu.edu.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, 72 E Concord St, Boston, MA, 02118, USA. malosco@bu.edu.
Source: Acta neuropathologica [Acta Neuropathol] 2025 Mar 06; Vol. 149 (1), pp. 24. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1432-0533
DOI:10.1007/s00401-025-02860-z