Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability.

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Title: Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability.
Authors: Curry RN; Department of Pediatrics, Baylor College of Medicine, Houston, TX.; Pediatric Neuro-Oncology Research Program, Texas Children's Hospital, Houston, TX.; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., McDonald MF; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.; Program in Development, Disease Models, and Therapeutics, Baylor College of Medicine, Houston, TX., He P; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX.; Program in Cancer Cell Biology, Baylor College of Medicine, Houston, TX, USA., Lozzi B; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX.; Program in Genetics and Genomics, Baylor College of Medicine, Houston, TX, USA., Ko Y; Program in Immunology and Microbiology, Baylor College of Medicine, Houston, TX, USA., O'Reilly I; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., Rosenbaum A; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., Kwon W; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., Fahim L; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Marcus J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Powell N; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Wang S; Department of Neurosurgery, Baylor College of Medicine, Houston, TX., Ma J; Cytogenetics and Cell Authentication Core, MD Anderson Cancer Center, Houston, TX., Multani A; Cytogenetics and Cell Authentication Core, MD Anderson Cancer Center, Houston, TX., Choi DJ; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., Sardar D; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX., Mohila C; Department of Neuropatholgy, Texas Children's Hospital, Houston, TX., Lee J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Gallo M; Pediatric Neuro-Oncology Research Program, Texas Children's Hospital, Houston, TX., Harmanci A; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX., Harmanci AS; Program in Genetics and Genomics, Baylor College of Medicine, Houston, TX, USA.; Program in Immunology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX., Deneen B; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX.; Program in Development, Disease Models, and Therapeutics, Baylor College of Medicine, Houston, TX.; Program in Cancer Cell Biology, Baylor College of Medicine, Houston, TX, USA.; Department of Neurosurgery, Baylor College of Medicine, Houston, TX.; Center for Cancer Neuroscience, Baylor College of Medicine, Houston, TX., Rao G; Department of Neurosurgery, Baylor College of Medicine, Houston, TX.; Center for Cancer Neuroscience, Baylor College of Medicine, Houston, TX.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 25. Date of Electronic Publication: 2025 Feb 25.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.02.20.639365