Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial.
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| Title: | Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial. |
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| Authors: | Phillips PPJ; UCSF Center for Tuberculosis and.; Department of Medicine, University of California, San Francisco, San Francisco, California., Peloquin CA; College of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, Florida., Sterling TR; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Kaur P; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts., Diacon AH; TASK, Cape Town, South Africa., Gotuzzo E; Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru., Benator D; Infectious Diseases Section, Washington DC Veterans Affairs Medical Center, George Washington University, Washington, District of Columbia., Warren RM; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Science, SAMRC Centre for Tuberculosis, Stellenbosch University, Cape Town, South Africa., Sikes D; Laboratory Branch, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia., Lecca L; Socios En Salud Sucursal Perú, Lima, Peru., Gandhi NR; Departments of Epidemiology, Global Health, and Medicine and Emory/Georgia Tuberculosis Research Advancement Center, Emory University, Atlanta, Georgia., Streicher EM; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Science, SAMRC Centre for Tuberculosis, Stellenbosch University, Cape Town, South Africa., Dianis N; Westat, Bethesda, Maryland., Eisenach K; TB or NOT TB Consulting, LLC, Little Rock, Arkansas., Mitnick CD; Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts; and., Horsburgh CR Jr; Departments of Epidemiology, Biostatistics, Global Health, and Medicine, Boston University Schools of Public Health and Medicine, Boston, Massachusetts. |
| Source: | American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2025 Jul; Vol. 211 (7), pp. 1277-1287. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1535-4970 |
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| DOI: | 10.1164/rccm.202407-1354OC |
