A pharmacological vasoconstrictor cocktail targeting endothelin signalling generates a stable, reproducible focal cerebral infarct with associated functional deficits in mice.

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Title: A pharmacological vasoconstrictor cocktail targeting endothelin signalling generates a stable, reproducible focal cerebral infarct with associated functional deficits in mice.
Authors: Law KC; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia; Charles Perkins Centre, The University of Sydney, Camperdown, Australia., Quattrocchi AT; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia., Xuereb BE; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia., Moriarty N; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia., Thompson LH; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia; Charles Perkins Centre, The University of Sydney, Camperdown, Australia., Parish CL; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia. Electronic address: cparish@unimelb.edu.au.
Source: Experimental neurology [Exp Neurol] 2025 Jun; Vol. 388, pp. 115215. Date of Electronic Publication: 2025 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2430
DOI:10.1016/j.expneurol.2025.115215