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Label-free Aβ plaque detection in Alzheimer's disease brain tissue using infrared microscopy and neural networks.

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Title: Label-free Aβ plaque detection in Alzheimer's disease brain tissue using infrared microscopy and neural networks.
Authors: Müller D; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Bioinformatics Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Bioinformatics, Germany., Röhr D; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany., Boon BDC; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands.; Mayo Clinic, Department of Neuroscience, Jacksonville, FL, USA., Wulf M; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Medical Proteome Analysis, Germany.; Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Germany., Arto T; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany., Hoozemans JJM; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands., Marcus K; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Medical Proteome Analysis, Germany.; Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Germany., Rozemuller AJM; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands., Großerueschkamp F; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany., Mosig A; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Bioinformatics Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Bioinformatics, Germany., Gerwert K; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany.
Source: Heliyon [Heliyon] 2025 Jan 18; Vol. 11 (4), pp. e42111. Date of Electronic Publication: 2025 Jan 18 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE
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  Data: Label-free Aβ plaque detection in Alzheimer's disease brain tissue using infrared microscopy and neural networks.
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  Data: <searchLink fieldCode="AU" term="%22Müller+D%22">Müller D</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Bioinformatics Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Bioinformatics, Germany.<br /><searchLink fieldCode="AU" term="%22Röhr+D%22">Röhr D</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany.<br /><searchLink fieldCode="AU" term="%22Boon+BDC%22">Boon BDC</searchLink>; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands.; Mayo Clinic, Department of Neuroscience, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wulf+M%22">Wulf M</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Medical Proteome Analysis, Germany.; Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Germany.<br /><searchLink fieldCode="AU" term="%22Arto+T%22">Arto T</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany.<br /><searchLink fieldCode="AU" term="%22Hoozemans+JJM%22">Hoozemans JJM</searchLink>; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Marcus+K%22">Marcus K</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Medical Proteome Analysis, Germany.; Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Germany.<br /><searchLink fieldCode="AU" term="%22Rozemuller+AJM%22">Rozemuller AJM</searchLink>; Amsterdam UMC, Amsterdam Neuroscience, Department of Pathology, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Großerueschkamp+F%22">Großerueschkamp F</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany.<br /><searchLink fieldCode="AU" term="%22Mosig+A%22">Mosig A</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Bioinformatics Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Bioinformatics, Germany.<br /><searchLink fieldCode="AU" term="%22Gerwert+K%22">Gerwert K</searchLink>; Ruhr University Bochum, Center for Protein Diagnostics (PRODI), Biospectroscopy Division, Germany.; Ruhr University Bochum, Faculty of Biology and Biotechnology, Department of Biophysics, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101672560%22">Heliyon</searchLink> [Heliyon] 2025 Jan 18; Vol. 11 (4), pp. e42111. <i>Date of Electronic Publication: </i>2025 Jan 18 (<i>Print Publication: </i>2025).
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              Text: 2025 Jan 18
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