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The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection.

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Title: The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection.
Authors: Woolsey C; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Cross RW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Chu VC; Gilead Sciences Inc., Foster City, CA, USA., Prasad AN; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Agans KN; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Borisevich V; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Deer DJ; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Harrison MB; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Martinez JK; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Dobias NS; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Fenton KA; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Cihlar T; Gilead Sciences Inc., Foster City, CA, USA., Nguyen AQ; Gilead Sciences Inc., Foster City, CA, USA., Babusis D; Gilead Sciences Inc., Foster City, CA, USA., Bannister R; Gilead Sciences Inc., Foster City, CA, USA., Vermillion MS; Gilead Sciences Inc., Foster City, CA, USA., Geisbert TW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.
Source: Science advances [Sci Adv] 2025 Mar 14; Vol. 11 (11), pp. eadw0659. Date of Electronic Publication: 2025 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection.
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  Data: <searchLink fieldCode="AU" term="%22Woolsey+C%22">Woolsey C</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Cross+RW%22">Cross RW</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chu+VC%22">Chu VC</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Prasad+AN%22">Prasad AN</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Agans+KN%22">Agans KN</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Borisevich+V%22">Borisevich V</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Deer+DJ%22">Deer DJ</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Harrison+MB%22">Harrison MB</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+JK%22">Martinez JK</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dobias+NS%22">Dobias NS</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Fenton+KA%22">Fenton KA</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Cihlar+T%22">Cihlar T</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+AQ%22">Nguyen AQ</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Babusis+D%22">Babusis D</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bannister+R%22">Bannister R</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vermillion+MS%22">Vermillion MS</searchLink>; Gilead Sciences Inc., Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Geisbert+TW%22">Geisbert TW</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA.
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