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Perivascular space and white matter hyperintensities in Alzheimer's disease: associations with disease progression and cognitive function.

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Title: Perivascular space and white matter hyperintensities in Alzheimer's disease: associations with disease progression and cognitive function.
Authors: Schirge PM; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Perneczky R; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Ageing Epidemiology (AGE) Research Unit, School of Public HealthImperial College London, London, UK., Taoka T; Department of Innovative Biomedical Visualization (iBMV), Graduate School of Medicine, Nagoya University, Nagoya, Japan., Ruiz-Rizzo AL; Department of Neurology, Jena University Hospital, Jena, Germany., Ersoezlue E; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; ECRC Experimental and Clinical Research Center, Charité- Universitätsmedizin Berlin, Berlin, Germany., Forbrig R; Institute of Neuroradiology, LMU Hospital, LMU Munich, Munich, Germany., Guersel S; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany., Kurz C; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany., Brendel M; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Department of Nuclear Medicine, Ludwig Maximilian University Hospital, Ludwig Maximilian University of Munich, Munich, Germany., Hellmann-Regen J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; ECRC Experimental and Clinical Research Center, Charité- Universitätsmedizin Berlin, Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany.; Department of Psychiatry, School of Medicine, Technical University of Munich, Munich, Germany.; University of Edinburgh, UK DRI, Edinburgh, UK., Schneider A; German Center for Neurodegenerative Diseases (DZNE)Venusberg-Campus, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Bonn, Germany., Jessen F; German Center for Neurodegenerative Diseases (DZNE)Venusberg-Campus, Bonn, Germany.; Department of Psychiatry, University of Cologne, Medical Faculty, Kerpener Strasse 62, 50924, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Buerger K; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), Ludwig Maximilian University Hospital, Ludwig Maximilian University, Munich, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, Section for Dementia Research, Hertie Institute for Clinical Brain Research and University of Tübingen, Tübingen, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité- Universitätsmedizin Berlin, Corporate Member of Freie Universität BerlinHumboldt-Universität zu Berlin-Institute of Psychiatry and Psychotherapy, Berlin, Germany., Spruth E; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany., Fliessbach K; German Center for Neurodegenerative Diseases (DZNE)Venusberg-Campus, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Bonn, Germany., Rostamzadeh A; Department of Psychiatry, University of Cologne, Medical Faculty, Kerpener Strasse 62, 50924, Cologne, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD), Ludwig Maximilian University Hospital, Ludwig Maximilian University, Munich, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, Germany., Sodenkamp S; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Ewers M; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), Ludwig Maximilian University Hospital, Ludwig Maximilian University, Munich, Germany., Rauchmann BS; Institute of Neuroradiology, LMU Hospital, LMU Munich, Munich, Germany. boris.rauchmann@med.uni-muenchen.de.; Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany. boris.rauchmann@med.uni-muenchen.de.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK. boris.rauchmann@med.uni-muenchen.de.; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany. boris.rauchmann@med.uni-muenchen.de.; Institute of Neuroradiology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, München, Germany. boris.rauchmann@med.uni-muenchen.de.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 Mar 18; Vol. 17 (1), pp. 62. Date of Electronic Publication: 2025 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1758-9193
DOI:10.1186/s13195-025-01707-9